Hi, I put an 8" Polk/MOMO MM2084 in my back quarter panel. 2001 Tahoe. Not all 8" will fit as it is not a very deep opening. I also added an aftermarket amp to power it. Sounds great! I believe though the factory sub is an 8" 2 ohm, not 4 ohm? All the other factory speakers in the Tahoe are 2 ohm.
Also, it is very easy to remove and replace the factory subwoofer back there. Let me know if you have any questions on this. I think I may have a diagram on how to remove the back to get at that subwoofer. I would recommend though to also look at getting an aftermarket amp to power the new sub. I don't think a new sub will sound much better just hooking it up to the factory stereo and amp.
I first tried just putting a new sub back then without an aftermarket amp and it sounded ok, not a big improvement since the sub takes a lot of power to move. But after I put my aftermarket amp in the Tahoe it sounds great.