Yes.
You will effectively be raising your final drive ratio with the taller tires and adding more rotating mass to the final drive.
You will lose torque in the ratio and acceleration by adding the mass.
The lift will make your aerodynamics suck also,and AT's or knobbys suck for cornering.
Think about it,taller tires,higher center of gravity.
And your gas mileage will drop also a bit.
Whether you lose alot or a little is relative to your opinion.
I wouldn't do it myself because of the loss,but i'm more GO than SHOW.
And you can regain it with mods later down the road,it's not a whole lot of a loss.
So if you can afford it and it makes you happy-do it.
33's aren't a huge tire,don't worry alot.